Why Low Sennoside Matters

The low-sennoside content in Cassia fistula extract is a key differentiator, ensuring gentle* yet effective bowel regulation* without the drawbacks of traditional stimulant laxatives. Ingredients with high-sennoside values can cause dependency, cramping, and digestive exhaustion. A low­-sennoside extract offers a safer, non-habit-forming solution suitable for long-term use. It provides smooth and natural support* without gripping or discomfort*, making it ideal for individuals seeking a milder approach to digestive wellness.

Comprehensive Clinical Evidence Across Multiple Age Groups

CaFi® is supported by FOUR human clinical studies — spanning pediatric, adult, older adult populations, and a direct comparison versus a standard stimulant laxative (senna). Across these studies, CaFi® consistently demonstrated statistically significant improvements in key measures of bowel function, including increased frequency of bowel movements, improved stool consistency, reduced straining, and relief from associated gastrointestinal symptoms.

CaFi® outperformed or differentiated itself from senna in tolerability, with subjects experiencing effective relief without the discomfort, urgency, or cramping commonly associated with stimulant laxatives. Across all studies, there were no clinically meaningful adverse effects on safety parameters.

This breadth of clinical validation — across multiple age groups and against an active comparator — positions CaFi® as one of the most comprehensively studied, family-friendly in the digestive health category.

CaFi® vs. Senna: Head to Head Clinical

Clinically studied effective as senna — without the cramping, urgency, or stimulant-related discomfort.
The Study: A randomized controlled trial comparing CaFi and Senna (Cassia angustafolia)

Study Participants: 60 healthy participants with irregular bowel habits consumed CaFi or Senna over a three-week period.

Results: CaFi (Cassia fistula extract) was as effective as Senna (Cassia angustifolia) in helping to increase the frequency of bowel movements and softening of stool.

Straining during defecation was significantly reduced with CaFi as compared to Senna.

CaFi worked faster vs. Senna, while associated symptoms such as headaches, bloating, and gaseous distension were also relieved.

CaFi group did not experience side effects like gripping, pain in abdomen, and exhaustion after defecation – all of which were observed in the Senna group.

Dosage and Use

CaFi is naturally palatable with a sweet taste to enhance formulation flexibility, allowing it to be incorporated into various supplement delivery formats.

Recommended Dosing: 250mg – 500mg